GENOTYPE-PHENOTYPE CORRELATION IN PHENYLKETONURIA

Genotype-phenotype correlation in phenylketonuria

Introduction.Phenylketonuria is an inborn metabolism error with a high phenotypical variability, due in part to the large number of implicated genetical variants (over 1200 reported) but also due to other factors.Establishing a genotype=phenotype correlation, accessible today through molecular testing, is an important instrument for diagnostical ac

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The challenges and opportunities of conducting a clinical trial in a low resource setting: The case of the Cameroon mobile phone SMS (CAMPS) trial, an investigator initiated trial

Abstract Conducting clinical trials in developing countries often presents significant ethical, organisational, cultural and infrastructural challenges to researchers, pharmaceutical companies, sponsors and regulatory bodies.Globally, these regions are under-represented in research, yet this population stands to gain more from research in these set

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Project lawmaking of higher legal education reform in Ukraine

The article considers the ways of reforming higher legal education in Ukraine and contains suggestions on its improvement.The author analyses the actual state of higher legal education in Ukraine and the most important methodological approaches to the content of legal Boot Hooks education in current state of social and legal development.The emphasi

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A FEAST Algorithm for the Linear Response Eigenvalue Problem

In Sleeves the linear response eigenvalue problem arising from quantum chemistry and physics, one needs to compute several positive eigenvalues together with the corresponding eigenvectors.For such a task, in this paper, we present a FEAST algorithm based on complex contour integration for the linear response eigenvalue problem.By simply dividing t

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